Industrial chemist with extensive experience in Medicinal Chemistry, Drug Discovery, Organic Synthesis, Technical Writing, cGMP, Chemical Hygiene and Lab Safety, and EPA & OSHA ComplianceMedicinal chemistry, process research and development, and organic synthesis.Drug discovery, including small molecule structure-based design and SAR optimization in collaboration with CADD, biology, ADMET, and informatics teams.Design and synthesis of complex organic compounds for medicinal applications.Rational, structure-based drug design and development.Design and execution of optimized, scalable, safe chemical processes for drug intermediates and APIs...

Biomedical Sciences Expert in Immunology Research, Autoimmune Diseases (Multiple Sclerosis, Uveitis, EAE and Disease Models), Neuroimmunology, Immune Regulation, Neuroimmune Interactions and Immune RegulationImmunology, neuro-immunology, immune regulation, autoimmunity and neuroscience research.Immune assays and immune cell isolations.In vivo animal models of autoimmune diseases.Mouse model studies in Autoimmune diseases and immunotherapy.Neuro-immune interactions, neuro-ImmunologyAutoimmune diseases and autoimmunity.Immune regulationRegulatory T CellsTh17 biologyAdvanced flow cytometerEAEMultiple sclerosisOcular immunologyMolecular biolog...

Physicist and Nanotechnologist Specialized in Probe/Atomic Force Microscopy, Biophysics, and Nanomedicine, Materials Science, and Pharmaceuticals.Nanotechnology research and development in biology and biophysics, neuroscience, materials science, physics, engineering and pharmaceuticals.Process strategy, data acquisition and analysis, client communication and reporting, in academic and corporate environments.Technical proficiency in many surface analytical techniques, clean room processing, and bio-lab practices.Designed and engineered (CAD) add-on modules for combined TIRF/AFM microscopy.

Ph. D. Protein Drug Products Expert including Enzymes, Antibodies and Antigens and the Purification and characterization of proteins and glycoproteins.Purification and characterization of proteins and glycoproteins.Protein and glycoprotein drug products including enzymes, antibodies and antigens.Enzymology - development of reliable, linear assays (colorimetric, fluorometric, radioactive), kinetic analysis of enzymatic reactions.Technical writing and editing (e.g., CMC sections of new drug applications, biological licensing agreements; technical reports, white papers, development reports, validation reports).Miscellaneous separation techniq...

Clinical Research and Medical Affairs Expert Physician (MD) Specializing in Global Drug and Biologics Development Clinical Expertise; Approval of Multiple Drugs in Small Molecules and Biologics.Clinical research and medical affairs physician (MD) specializing in global drug and biologics development, approval of small molecules drugs and biologics.Commercial development, including Clinical Development Plans (CDPs) due diligence, business cases, and marketing support and protocols for Phase I-IV as well as post-marketing studies.Respected authority and resource working with key opinion leaders in a diverse range of pharmaceutical and medi...

Medicinal Chemistry Consultant, Experienced Expert Witness, and Patent Agent Specializing in Drug Discovery, Drug Design, Intellectual Property Rights, Patent Application and ProsecutionTechnical ExpertiseMedicinal chemistryDrug discovery and developmentHit to lead optimizationStructure based drug designFragment based drug designMolecular modelingBiological TargetsVoltage gates ion channelsLigand gated ion channelsG protein-coupled receptorsKinasesTyrosine phosphatasesMetalloproteasesDisease StatesCardiovascular diseaseOncologyChronic pain and inflammationNeurodegenerative diseaseOsteoporosisArthritisIntellectual Property ExpertiseRegister...

Small Molecule Drug Development and Manufacturing Expert with Extensive Biotechnology ExperienceSummaryDrug development from proof-of-concept to commercialization in early to mid stage biotech and large pharmaceutical companies.Extensive background in biotechnology and small molecule development, manufacturing, quality, analytical, regulatory, outsourcing, project management and business development. ServicesMarketed products: Biotech Products: Remicade (infliximab), Simponi (golimumab), Retavase (reteplase), Eprex (epoetin), ReoPro. Small Molecule: Patanol, Azopt and Volfenol%uFFFF.Development drugs: Large molecules: AntiIL5, AntiTNF,...

Medical Chemist Specializing in Synthetic, Chemistry, Medicinal Chemistry and Due Diligence Evaluation of Preclinical Packaging. Drug Licensing for Clinical Development, Pre-IND, (Pre-Investigational New Drug Application), With an Emphasis on Early Clinical Trials, Prior to Out licensing CompoundsMedical Chemist specializing in synthetic, chemistry, medicinal chemistry and due diligence evaluation of preclinical packaging.Drug licensing for clinical development, pre-IND, (Pre-Investigational New Drug Application), with an emphasis on early clinical trials, prior to out licensing compounds.Identification of clinical candidates for potential...

Pharmaceutical Molecular Modeling Expert in Ligand-Based and Structure-Based Design, and Structural Bioinformatics. Pharmacophore Modeling for Muscarinic AgonistsMolecular modeler in ligand-based and structure-based design, including structural bioinformatics.Provide scientific content for the protein folding and 3D drug design modules.Establish criteria for compounds through CADD/NMR (Computer-Aided Design and Drafting/Nuclear Magnetic Resonance Spectroscopy).Pharmacophore modeling for muscarinic agonists that was developed through phase II clinical trials.

Medicinal Chemist with Diversified Drug Discovery and Development BackgroundA Medicinal Chemist with an extensive and diversified background in drug discovery.Discovery of a smallpox inhibitor utilized in major biodefense agencies.Computer aided drug design and creative applications of organic chemistry.Implements and manages database solutions and robotic applications.Key CompetenciesCMC and IND support.Drug discovery.Chemical development.Establishing and managing robotic solutions.Managing complex scientific instruments.Team leadership and coordination, building effective project teams.Implementing and managing database solutions.NMR (Nu...